Feasibility of diffusion‐weighted imaging in the differentiation of metastatic from nonmetastatic lymph nodes: Early experience
- 5 September 2008
- journal article
- research article
- Published by Wiley in Journal of Magnetic Resonance Imaging
- Vol. 28 (3), 714-719
- https://doi.org/10.1002/jmri.21480
Abstract
Purpose To investigate the feasibility of diffusion‐weighted imaging (DWI) in the differentiation of metastatic from nonmetastatic lymph nodes. Materials and Methods In 125 patients who underwent lymph node dissection for uterine cervical cancer, DWI was performed at b value of 0 and 1000 s/mm2. By referring to the surgical maps of the pelvic lymph nodes, the apparent diffusion coefficient (ADC) was compared in the metastatic and nonmetastatic lymph nodes, and receiver‐operating‐characteristics analysis was performed to evaluate the diagnostic performance of the ADC in differentiating metastatic from nonmetastatic lymph nodes. Results The ADC were significantly lower in the metastatic lymph nodes (0.7651 × 10−3 mm2/s ± 0.1137) than in the nonmetastatic lymph nodes (1.0021 × 10−3 mm2/s ± 0.1859; P < 0.001). The area‐under‐the‐curve of ADC for differentiating metastatic from nonmetastatic lymph nodes, was 0.902. The sensitivity and specificity of ADC for differentiating metastatic from nonmetastatic lymph nodes, were 87% for the ADC and 80%, respectively. Conclusion DWI is feasible for differentiating metastatic from nonmetastatic lymph nodes in patients with uterine cervical cancer. J. Magn. Reson. Imaging 2008;28:714–719.Keywords
This publication has 26 references indexed in Scilit:
- Functional MR Imaging of Prostate CancerRadioGraphics, 2007
- MRI for Pretreatment Lymph Node Staging in Uterine Cervical CancerAmerican Journal of Roentgenology, 2006
- Comparison of the accuracy of magnetic resonance imaging and positron emission tomography/computed tomography in the presurgical detection of lymph node metastases in patients with uterine cervical carcinomaCancer, 2006
- Apparent diffusion coefficient in cervical cancer of the uterus: comparison with the normal uterine cervixEuropean Radiology, 2004
- Multivariate analysis of histopathologic prognostic factors for invasive cervical cancer treated with radical hysterectomy and systematic retroperitoneal lymphadenectomyActa Obstetricia et Gynecologica Scandinavica, 2002
- Comparison of Dynamic Helical CT and Dynamic MR Imaging in the Evaluation of Pelvic Lymph Nodes in Cervical CarcinomaAmerican Journal of Roentgenology, 2000
- Interest of Pelvic and Paraaortic Lymphadenectomy in Patients with Stage IB and II Cervical CarcinomaGynecologic Oncology, 1999
- Diffusion-weighted MR imaging with a single-shot echoplanar sequence: detection and characterization of focal hepatic lesions.American Journal of Roentgenology, 1998
- Staging of Invasive Cervical Carcinoma and of Pelvic Lymph Nodes by High Resolution MRI with a Phased-Array Coil in Comparison with Pathological FindingsJournal of Computer Assisted Tomography, 1998
- Uterine cervical carcinoma: evaluation of pelvic lymph node metastasis with MR imaging.Radiology, 1994