Guillain-Barre Syndrome, Influenza, and Influenza Vaccination: The Epidemiologic Evidence
- 9 January 2014
- journal article
- review article
- Published by Oxford University Press (OUP) in Clinical Infectious Diseases
- Vol. 58 (8), 1149-1155
- https://doi.org/10.1093/cid/ciu005
Abstract
Guillain-Barré syndrome (GBS) is the most common cause of acute flaccid paralysis worldwide, and is thought to be immune-mediated. It is preceded by upper respiratory or gastrointestinal infection in about two-thirds of cases and is associated with some viral infections, including influenza. GBS has also been associated with the 1976 swine-influenza vaccine. Thereafter, some studies have shown a small increased risk of GBS following receipt of seasonal and 2009 H1N1 monovalent influenza vaccines. Studies over the years have also shown an increased risk of GBS following influenza infection, and the magnitude of risk is several times greater than that following influenza vaccination. Because GBS is rare, and even rarer following vaccination, it is difficult to estimate precise risk. We try to shed light on the complex relationship of GBS and its association with influenza and influenza vaccines over the past 35 years.This publication has 33 references indexed in Scilit:
- Guillain-Barré Syndrome Incidence in a Large United States Cohort (2000–2009)Neuroepidemiology, 2012
- Guillain–Barré SyndromeThe New England Journal of Medicine, 2012
- Population Incidence of Guillain-Barré Syndrome: A Systematic Review and Meta-AnalysisNeuroepidemiology, 2011
- Guillain-Barré syndrome after exposure to influenza virusThe Lancet Infectious Diseases, 2010
- The Epidemiology of Guillain-Barré Syndrome WorldwideNeuroepidemiology, 2008
- Infections à Campylobacter jejuni et à cytomégalovirus (CMV) associées au syndrome de Guillain-Barré (SGB)Archives de Pédiatrie, 2006
- Influenza,CampylobacterandMycoplasmaInfections, and Hospital Admissions for Guillain-Barré Syndrome, EnglandEmerging Infectious Diseases, 2006
- Guillain-Barré syndromeThe Lancet, 2005
- The spectrum of antecedent infections in Guillain-Barré syndromeNeurology, 1998
- GUILLAIN-BARRE SYNDROME FOLLOWING VACCINATION IN THE NATIONAL INFLUENZA IMMUNIZATION PROGRAM, UNITED STATES, 1976–19771American Journal of Epidemiology, 1979