Present and Future of Surface-Enhanced Raman Scattering

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Abstract
The discovery in 1974 of the enhancement of Raman scattering by molecules adsorbed on nanostructured metal surfaces is considered a landmark in the history of spectroscopic and analytical techniques. Much experimental and theoretical effort has been spent toward understanding the surface enhanced Raman scattering (SERS) effect, and demonstrating its potential toward various types of ultrasensitive sensing applications in a wide variety of fields. Forty five years later, SERS has blossomed as an extremely rich area of research and technology, but additional efforts are still needed before it can be routinely used as a commercial product. In this Review, prominent authors from all over the world joined efforts to summarize the current state-of-the-art in understanding and using SERS, as well as to propose what can be expected in the near future, in terms of research, applications, and technological development.
Funding Information
  • Division of Chemistry (CHE-1414466, CHE-1503408, CHE-1707859, CHE-1807269)
  • Defense Advanced Research Projects Agency (DARPA-16-35-INTERCEPT-FP-018)
  • Knut och Alice Wallenbergs Stiftelse
  • Department of Science and Technology, Ministry of Science and Technology (SR/NM/NS-23/2016)
  • Office of Naval Research (N00014-18-1-2876)
  • Villum Fonden (9301)
  • Royal Society of New Zealand
  • National Natural Science Foundation of China (21633005, 21705015)
  • Engineering and Physical Sciences Research Council (EP/L014165/1, EP/L027151/1, EP/P034063/1)
  • Bundesministerium für Bildung und Forschung (13GW0096F)
  • Hokkaido University
  • Danmarks Grundforskningsfond (DNRF122)
  • Ministry of Science and Technology of the People's Republic of China (2017YFA0206902)
  • Ministry of Education - Singapore (RG11/18)
  • Ministerio de Economía y Competitividad (CTQ2017-88648-R, MAT2016-77809-R)
  • National Research Foundation of Korea (2019R1A2C3004375)
  • Deutsche Forschungsgemeinschaft (EXC 2089/1 – 390776260, SCHL 594/13-1, SFB 1278)
  • FP7 Ideas: European Research Council (259432)
  • H2020 European Research Council (772108, 787510, 789104)
  • Biotechnology and Biological Sciences Research Council (BB/L014823/1)
  • Ministry of Science, ICT and Future Planning (H-GUARD_2013M3A6B2078947)
  • Agencia Estatal de Investigación (MDM-2017-0720)
  • Departamento de Educación, Gobierno Vasco (IT1164-19)