Enteroviral meningitis in children in Turkey
Open Access
- 1 June 2009
- journal article
- Published by Walter de Gruyter GmbH in Open Medicine
- Vol. 4 (2), 253-258
- https://doi.org/10.2478/s11536-008-0055-5
Abstract
In the indexed medical literature, there have been a very limited number of studies to investigate the epidemiologic and clinical features of enteroviral meningitis in Turkey. The aim of the present retrospective study is to update the actual situation to recognize the spectrum and magnitude of this important clinical entity. Between June 1999 and December 2004, 612 cases of aseptic meningitis were followed up at our hospital. Enteroviral meningitis was defined by isolation of enteroviruses from cerebrospinal fluid (CSF) and/or stool samples. Mumps virus was detected in 310 cases (50.7%) and enteroviruses were the etiologic agents in 104 (17%) of the patients with aseptic meningitis. Most of the enteroviral meningitis cases (36 cases, 34.6%) were diagnosed in August and 70 (67.3%) of them were male. The mean age was 5.6 ± 3.4 years. The most common initial symptoms were fever (81.7%), vomiting (77.9%) and headache (57.7%). In the physical examination, 46.2% of the cases had neck stiffness and 38.5% had pharyngitis. Echovirus 30 was the most frequently (38 cases, 36.5%) isolated enterovirus with peaks in 1999, 2002 and 2004. The other frequently isolated enteroviruses were Coxsackie virus type B (17 cases, 16.3%), echovirus 6 (11 cases, 10.6%), echovirus 11 (6 cases, 5.8%), and echovirus 13 (4 cases, 3.8 %). Mean hospitalization time was 6.2 ± 2.4 days. All patients recovered without any sequelae. Enteroviruses have an important role in childhood aseptic meningitis cases in Turkey too, and the predominant serotypes vary according to years.Keywords
This publication has 30 references indexed in Scilit:
- Molecular typing of enteroviruses associated with viral meningitis in Cyprus, 2000–2002Journal of Medical Microbiology, 2006
- Paediatric Investigators Collaborative Network on Infections in Canada (PICNIC) study of aseptic meningitisBMC Infectious Diseases, 2006
- Echovirus 30, Jiangsu Province, ChinaEmerging Infectious Diseases, 2005
- Multiple-Year Experience in the Diagnosis of Viral Central Nervous System Infections with a Panel of Polymerase Chain Reaction Assays for Detection of 11 VirusesClinical Infectious Diseases, 2004
- Prospective Investigation of a Large Outbreak of Meningitis Due to Echovirus 30 During Summer 2000 in Marseilles, FranceMedicine, 2004
- Outbreak of Echovirus 30 Meningitis in SwitzerlandScandinavian Journal of Infectious Diseases, 1999
- Epidemiological features of entero non-poliovirus isolations in Belgium 1980–94Epidemiology and Infection, 1997
- Enteroviral Infections of the Central Nervous SystemClinical Infectious Diseases, 1995
- Diagnosis of enteroviral central nervous system infection by polymerase chain reaction during a large community outbreakThe Pediatric Infectious Disease Journal, 1994
- Echovirus Type 30 Infection Associated with Aseptic Meningitis in Nassau County, New York, USAIntervirology, 1993