{\rtf1\ansi\ansicpg1250\deff0\deflang1038\deflangfe1038\deftab708{\fonttbl{\f0\froman\fprq2\fcharset238{\*\fname Times New Roman;}Times New Roman CE;}} \viewkind4\uc1\pard\f0\fs24 N-ras mutation in a canine lymphoma: Short communication \par}

Abstract

Lymphomas of dogs were investigated by molecular genetic methods. Regions of exon 1 and 2 of the N-ras gene, which harbours the mutation hot spots (codons 12, 13 and 61) were screened. A GGT Ţ GAT (glycine Ţ aspartic acid) mutation in codon 13 was present in a multicentric-type lymphoma of a 1-year-old male dog.