Abstract
This commentary is focusing on novel aspects on the secreted CgA- and SgII-derived peptides, vasostatin-I (bovine and human CgA1–76, VS-I), WE-14 (CgA316–329), catestatin (bovine CgA344–366, human CgA352–372, Cts) and the SgII-derived secretoneurin (SgII180–204) as significant regulators of inflammatory reactions.