Evaluation of the Epidemiologic Utility of Secondary Typing Methods for Differentiation ofMycobacterium tuberculosisIsolates
Open Access
- 1 June 2003
- journal article
- research article
- Published by American Society for Microbiology in Journal of Clinical Microbiology
- Vol. 41 (6), 2683-2685
- https://doi.org/10.1128/jcm.41.6.2683-2685.2003
Abstract
Spoligotyping and mycobacterial interspersed repetitive unit-variable-number tandem repeat analysis (MIRU-VNTR) were evaluated for the ability to differentiate 64 Mycobacterium tuberculosis isolates from 10 IS6110-defined clusters. MIRU-VNTR performed slightly better than spoligotyping in reducing the number of clustered isolates and the sizes of the clusters. All epidemiologically related isolates remained clustered by MIRU-VNTR but not by spoligotyping.Keywords
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