Lifetime Nonnarcotic Analgesic Use and Decline in Renal Function in Women
Open Access
- 26 July 2004
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Internal Medicine
- Vol. 164 (14), 1519-1524
- https://doi.org/10.1001/archinte.164.14.1519
Abstract
Analgesic use is common in the general population, particularly among women.1 Analgesics may impair kidney function by altering prostaglandin production,2 causing interstitial nephritis,3 or potentially through a direct toxic effect on the tubular epithelium. However, limited and inconsistent information is available on the long-term effects of aspirin, other nonsteroidal anti-inflammatory drugs (NSAIDs), and acetaminophen on renal function.Keywords
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