Health-related quality of life, employment and disability in patients with Sjögren's syndrome
Open Access
- 24 June 2009
- journal article
- research article
- Published by Oxford University Press (OUP) in Rheumatology
- Vol. 48 (9), 1077-1082
- https://doi.org/10.1093/rheumatology/kep141
Abstract
Objective. To compare health-related quality of life (HR-QOL), employment and disability of primary and secondary SS (pSS and sSS, respectively) patients with the general Dutch population. Methods. HR-QOL, employment and disability were assessed in SS patients regularly attending the University Medical Center Groningen (n = 235). HR-QOL, employment and disability were evaluated with the Short Form-36 questionnaire (SF-36) and an employment and disability questionnaire. Results were compared with Dutch population data (matched for sex and age). Demographical and clinical data associated with HR-QOL, employment and disability were assessed. Results. Response rate was 83%. SS patients scored lower on HR-QOL than the general Dutch population. sSS patients scored lower on physical functioning, bodily pain and general health than pSS patients. Predictors for reduced HR-QOL were fatigue, tendomyalgia, articular involvement, use of artificial saliva, use of anti-depressants, comorbidity, male sex and eligibility for disability compensation (DC). Employment was lower and DC rates were higher in SS patients compared with the Dutch population. Conclusion. SS has a large impact on HR-QOL, employment and disability.Keywords
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