The effect of dairy foods on CHD: a systematic review of prospective cohort studies
- 17 August 2009
- journal article
- review article
- Published by Cambridge University Press (CUP) in British Journal of Nutrition
- Vol. 102 (9), 1267-1275
- https://doi.org/10.1017/s0007114509371664
Abstract
There is interest in the degree to which fats in dairy foods contribute to CHD. We undertook a systematic review to investigate the effect of dairy consumption on CHD using prospective cohort studies. A systematic search of electronic databases identified studies relating dairy food intake in adulthood to episodes or death from CHD, IHD and myocardial infarction. Included studies were assessed for quality based on study methodology, validity of dietary assessment, success of follow-up, standardised assessment of CHD, IHD or myocardial infarction end points and appropriateness of statistical adjustment. Data from twelve cohorts involving >280000 subjects were included. Most studies had follow-up of >80%, adjusted statistically for three or more confounders and used standard criteria to determine end points. About half the studies used a validated FFQ, administered the FFQ more than once or had follow-up of >20 years. Fewer than half the studies involved subjects representative of the general population. Four of the twelve cohorts found no association between dairy intake and CHD. Eight studies reported varying relationships between different dairy foods and CHD or differential associations based on race, sex or over time. Although dairy foods contribute to the SFA composition of the diet, this systematic review could find no consistent evidence that dairy food consumption is associated with a higher risk of CHD. This could be due to the limited sensitivity of the dietary assessment methods to detect an effect of a single food in a mixed diet on complex clinical outcomes.Keywords
This publication has 59 references indexed in Scilit:
- Diet and Lifestyle Recommendations Revision 2006Cell Metabolism, 2006
- Dietary Intake of Calcium in Relation to Mortality From Cardiovascular DiseaseStroke, 2006
- Dairy fat in cheese raises LDL cholesterol less than that in butter in mildly hypercholesterolaemic subjectsEuropean Journal of Clinical Nutrition, 2005
- Milk consumption, stroke, and heart attack risk: evidence from the Caerphilly cohort of older menJournal of Epidemiology and Community Health, 2005
- Associations of Dietary Protein with Disease and Mortality in a Prospective Study of Postmenopausal WomenAmerican Journal of Epidemiology, 2005
- Milk drinking, ischaemic heart disease and ischaemic stroke I. Evidence from the Caerphilly cohortEuropean Journal of Clinical Nutrition, 2004
- Milk, coronary heart disease and mortalityJournal of Epidemiology and Community Health, 2001
- Effect of Dietary Calcium and Milk Consumption on Risk of Thromboembolic Stroke in Older Middle-aged MenStroke, 1996
- Milk, butter, and heart disease.BMJ, 1991
- Is milk a coronary health hazard?Journal of Epidemiology and Community Health, 1977