Safety and side effects of the insulin analogues
- 22 December 2005
- journal article
- review article
- Published by Informa Healthcare in Expert Opinion on Drug Safety
- Vol. 5 (1), 131-143
- https://doi.org/10.1517/14740338.5.1.131
Abstract
The analogue insulins were developed to more clearly mimic the basal and prandial components of insulin secretion for subjects with diabetes mellitus. Analogues are now widely used and have largely taken over from the conventional human recombinant insulins. It is important that these insulins are not only as effective as their predecessors, but are also safe and well-tolerated. In this manuscript, the authors review the adverse effects reported with analogue insulins and make a comparison with standard insulin treatments.Keywords
This publication has 89 references indexed in Scilit:
- Insulin AnaloguesThe New England Journal of Medicine, 2005
- A review of basal insulinsDiabetic Medicine, 2003
- Variability of Insulin Absorption and Insulin ActionDiabetes Technology & Therapeutics, 2002
- Insulin analoguesThe Lancet, 1997
- The History of InsulinDiabetes Care, 1993
- The Effect of Intensive Treatment of Diabetes on the Development and Progression of Long-Term Complications in Insulin-Dependent Diabetes MellitusThe New England Journal of Medicine, 1993
- Subcutaneous Insulin Absorption Explained by Insulin's Physicochemical Properties: Evidence From Absorption Studies of Soluble Human Insulin and Insulin Analogues in HumansDiabetes Care, 1991
- Monomeric Insulins and Their Experimental and Clinical ImplicationsDiabetes Care, 1990
- The Physiologic Replacement of InsulinThe New England Journal of Medicine, 1989
- Insulin PharmacokineticsDiabetes Care, 1984