Screening for Multiple Endocrine Neoplasia Type 2A with DNA-Polymorphism Analysis
- 12 October 1989
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 321 (15), 996-1001
- https://doi.org/10.1056/nejm198910123211502
Abstract
Multiple endocrine neoplasia type 2a has been shown to be genetically linked to a locus near the centromere of chromosome 10. The availability of polymorphic DNA probes for the region permits the use of restriction-fragment–length polymorphisms (RFLP) to identify carriers of the gene for this cancer syndrome.Keywords
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