Design of Potent Inhibitors for Human Brain Memapsin 2 (β-Secretase)
- 23 March 2000
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 122 (14), 3522-3523
- https://doi.org/10.1021/ja000300g
Abstract
No abstract availableThis publication has 15 references indexed in Scilit:
- Human aspartic protease memapsin 2 cleaves the β-secretase site of β-amyloid precursor proteinProceedings of the National Academy of Sciences of the United States of America, 2000
- Purification and cloning of amyloid precursor protein β-secretase from human brainNature, 1999
- Identification of a Novel Aspartic Protease (Asp 2) as β-SecretaseMolecular and Cellular Neuroscience, 1999
- β-Secretase Cleavage of Alzheimer's Amyloid Precursor Protein by the Transmembrane Aspartic Protease BACEScience, 1999
- Cellular mechanisms of β-amyloid production and secretionProceedings of the National Academy of Sciences of the United States of America, 1999
- The cell biology of β-amyloid precursor protein and presenilin in Alzheimer's diseaseTrends in Cell Biology, 1998
- Transition-State Mimetics for HIV Protease Inhibitors: Stereocontrolled Synthesis of Hydroxyethylene and Hydroxyethylamine Isosteres by Ester-Derived Titanium Enolate Syn and Anti-Aldol ReactionsThe Journal of Organic Chemistry, 1998
- [18] Design of symmetry-based, peptidomimetic inhibitors of human immunodeficiency virus proteaseMethods in Enzymology, 1994
- [17] Design of tight-binding human immunodeficiency virus type 1 protease inhibitorsMethods in Enzymology, 1994
- Iodination of aryltrimethylsilanes. A mild approach to (iodophenyl)alanineThe Journal of Organic Chemistry, 1986