The significance of Epstein Barr Virus (EBV) & DNA Topoisomerase II alpha (DNA-Topo II alpha) immunoreactivity in normal oral mucosa, Oral Epithelial Dysplasia (OED) and Oral Squamous Cell Carcinoma (OSCC)
Open Access
- 1 January 2008
- journal article
- Published by Springer Science and Business Media LLC in Diagnostic Pathology
- Vol. 3 (1), 45
- https://doi.org/10.1186/1746-1596-3-45
Abstract
Head and neck cancer including oral cancer is considered to develop by accumulated genetic alterations and the major pathway is cancerization from lesions such as intraepithelial dysplasia in oral leukoplakia and erythroplakia. The relationship of proliferation markers with the grading of dysplasia is uncertain. The involvement of EBV in oral carcinogenesis is not fully understood.This publication has 55 references indexed in Scilit:
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