Non-Invasive Electromagnetic Skin Patch Sensor to Measure Intracranial Fluid–Volume Shifts
Open Access
- 29 March 2018
- Vol. 18 (4), 1022
- https://doi.org/10.3390/s18041022
Abstract
Elevated intracranial fluid volume can drive intracranial pressure increases, which can potentially result in numerous neurological complications or death. This study’s focus was to develop a passive skin patch sensor for the head that would non-invasively measure cranial fluid volume shifts. The sensor consists of a single baseline component configured into a rectangular planar spiral with a self-resonant frequency response when impinged upon by external radio frequency sweeps. Fluid volume changes (10 mL increments) were detected through cranial bone using the sensor on a dry human skull model. Preliminary human tests utilized two sensors to determine feasibility of detecting fluid volume shifts in the complex environment of the human body. The correlation between fluid volume changes and shifts in the first resonance frequency using the dry human skull was classified as a second order polynomial with R2 = 0.97. During preliminary and secondary human tests, a ≈24 MHz and an average of ≈45.07 MHz shifts in the principal resonant frequency were measured respectively, corresponding to the induced cephalad bio-fluid shifts. This electromagnetic resonant sensor may provide a non-invasive method to monitor shifts in fluid volume and assist with medical scenarios including stroke, cerebral hemorrhage, concussion, or monitoring intracranial pressure.Keywords
Funding Information
- National Aeronautics and Space Administration (NNX16AQ99A)
This publication has 32 references indexed in Scilit:
- Bound charges and currentsAmerican Journal of Physics, 2013
- American Medical Society for Sports Medicine position statement: concussion in sportBritish Journal of Sports Medicine, 2012
- Intracranial Pressure Monitoring: Invasive versus Non-Invasive Methods—A ReviewCritical Care Research and Practice, 2012
- Animal model for sport-related concussion; ICP and cognitive functionActa Neurologica Scandinavica, 2011
- Second Impact Syndrome: Concussion and Second Injury Brain ComplicationsJournal of the American College of Surgeons, 2010
- The effect of brain hematoma location on volumetric inductive phase shift spectroscopy of the brain with circular and magnetron sensor coils: a numerical simulation studyPhysiological Measurement, 2008
- A magnetic induction tomography system for samples with conductivities below 10 S m−1Measurement Science and Technology, 2008
- In Vivo Inductive Phase Shift Measurements to Detect Intraperitoneal FluidIEEE Transactions on Biomedical Engineering, 2007
- Biological tissue characterization by magnetic induction spectroscopy (MIS): requirements and limitationsIEEE Transactions on Biomedical Engineering, 2003
- Cerebrospinal fluid pulse pressure and intracranial volume-pressure relationships.Journal of Neurology, Neurosurgery & Psychiatry, 1979