PBPK modelling of inter-individual variability in the pharmacokinetics of environmental chemicals
- 30 December 2010
- journal article
- review article
- Published by Elsevier BV in Toxicology
- Vol. 278 (3), 256-267
- https://doi.org/10.1016/j.tox.2010.06.007
Abstract
No abstract availableKeywords
This publication has 114 references indexed in Scilit:
- Cell-Based Multiscale Computational Modeling of Small Molecule Absorption and Retention in the LungsPharmaceutical Research, 2010
- Whole-body physiologically based pharmacokinetic population modelling of oral drug administration: inter-individual variability of cimetidine absorptionJournal of Pharmacy and Pharmacology, 2009
- Population-Based Mechanistic Prediction of Oral Drug AbsorptionThe AAPS Journal, 2009
- Computational Toxicology of Chloroform: Reverse Dosimetry Using Bayesian Inference, Markov Chain Monte Carlo Simulation, and Human Biomonitoring DataEnvironmental Health Perspectives, 2008
- Methods To Evaluate Biliary Excretion of Drugs in Humans: An Updated ReviewMolecular Pharmaceutics, 2006
- Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cellsBiochemical and Biophysical Research Communications, 1991
- Nonparametric maximum likelihood estimation for population pharmacokinetics, with application to cyclosporineJournal of Pharmacokinetics and Biopharmaceutics, 1988
- Prediction of the volumes of distribution of basic drugs in humans based on data from animalsJournal of Pharmacokinetics and Biopharmaceutics, 1984
- Physiological pharmacokinetics of ethoxybenzamide based on biochemical data obtainedin vitro as well as on physiological dataJournal of Pharmacokinetics and Biopharmaceutics, 1982
- In vitro andin vivo evaluation of the tissue-to-blood partition coefficient for physiological pharmacokinetic modelsJournal of Pharmacokinetics and Biopharmaceutics, 1982