Reversing the Enantioselectivity of a Peptidic Catalyst by Changing the Solvent
- 2 February 2011
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 2011 (04), 499-502
- https://doi.org/10.1055/s-0030-1259523
Abstract
The enantioselectivity of the peptidic catalyst H-Pro-Pro-Asp-NH(CH2)11CH3 is reversed in different solvents. One enantiomer forms preferentially in pure DMSO or MeOH, whereas the other is preferentially formed in mixtures of water with DMSO or MeOH.Keywords
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