Enantioselective Recognition in Biomimetic Single Artificial Nanochannels
- 2 May 2011
- journal article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 133 (20), 7644-7647
- https://doi.org/10.1021/ja2004939
Abstract
Efficient enantiomer discrimination with a convenient system remains a challenge in the fields of biochemistry, medical science, and pharmaceutics. Here we report a simple enantioselective sensing device based on a single artificial β-cyclodextrin-modified nanochannel system. This nanodevice shows highly selective recognition of histidine enantiomers through monitoring of ionic current signatures.Keywords
This publication has 48 references indexed in Scilit:
- Chiral discrimination in biomimetic systems: PhenylalanineJournal of Chemical Sciences, 2007
- Bioinspired Chemical Inversion of l-Amino Acids to d-Amino AcidsJournal of the American Chemical Society, 2007
- A Practical Approach to the Resolution of Racemic N‐Benzyl α‐Amino Acids by Liquid–Liquid Extraction with a Lipophilic Chiral Salen–Cobalt(III) ComplexAngewandte Chemie, 2006
- Chiral nanotechnologyChirality, 2005
- Enantioselective Pharmacokinetics of Ibuprofen and Involved MechanismsDrug Metabolism Reviews, 2005
- Chiral Recognition of Dipeptides in a Biomembrane ModelJournal of the American Chemical Society, 2004
- Enantioselective transport of amino acids as their potassium and sodium salts by optically active diaza-18-crown-6 ethers having arene sidearmsTetrahedron: Asymmetry, 2004
- Guanidinium Receptors as Enantioselective Amino Acid Membrane CarriersJournal of the American Chemical Society, 2003
- A metal complex that binds α-amino acids with high and predictable stereospecificityNature, 1999
- Chemical asymmetric synthesisNature, 1989