Equipoise Lost: Ethics, Costs, and the Regulation of Cancer Clinical Research
- 10 June 2010
- journal article
- research article
- Published by American Society of Clinical Oncology (ASCO) in Journal of Clinical Oncology
- Vol. 28 (17), 2925-2935
- https://doi.org/10.1200/jco.2009.27.5404
Abstract
Cancer is the leading cause of death in Americans younger than 85 years of age and kills one American every 56 seconds. Advances in understanding of cancer biology have given us the potential to de...Keywords
This publication has 60 references indexed in Scilit:
- Gefitinib or Carboplatin–Paclitaxel in Pulmonary AdenocarcinomaNew England Journal of Medicine, 2009
- Steps and Time to Process Clinical Trials at the Cancer Therapy Evaluation ProgramJournal of Clinical Oncology, 2009
- The changing face of Phase 1 cancer clinical trialsCancer, 2009
- Do we want more cancer patients on clinical trials If so, what are the barriers to greater accrualTrials, 2008
- Development of Clinical Trials in a Cooperative Group Setting: The Eastern Cooperative Oncology GroupClinical Cancer Research, 2008
- Gefitinib plus best supportive care in previously treated patients with refractory advanced non-small-cell lung cancer: results from a randomised, placebo-controlled, multicentre study (Iressa Survival Evaluation in Lung Cancer)The Lancet, 2005
- Erlotinib in Previously Treated Non–Small-Cell Lung CancerNew England Journal of Medicine, 2005
- The Cancer Research UK experience of pre-clinical toxicology studies to support early clinical trials with novel cancer therapiesEuropean Journal Of Cancer, 2004
- The price of innovation: new estimates of drug development costsJournal of Health Economics, 2003
- Equipoise and the Ethics of Clinical ResearchNew England Journal of Medicine, 1987