The Anemia of Acute Renal Failure: Association with Oliguria and Elevated Blood Urea
- 1 January 1994
- journal article
- research article
- Published by Taylor & Francis Ltd in Renal Failure
- Vol. 16 (1), 125-131
- https://doi.org/10.3109/08860229409044854
Abstract
Anemia is very frequent in patients with acute failure but the nature of the relationship between the two conditions has remained unclear. We studied all patients with well-documented acute renal failure seen in consultation by our nephrology division during 1991. Fifty-three of the 56 patients had at least mild anemia (hematocrit < 35%) at some point during their hospital stay. Forty-three of the patients had a hematocrit below 30% and 14 had a hematocrit below this level on admission. Twenty-four of the patients underwent mujor operations and all of these patients required blood transfusions. In this group there was a significant correlation between maximum serum urea and lowest hemoglobin (r = 0.4, p <. 05) but no similar correlation between maximum creatinine and lowest hemoglobin. Oliguric patients had a mean lowest hemoglobin of 7.3 ± 0.4 g/dL., which was significantly lower than the value for nonoliguric patients, 9.0 ± 0.4 g /dL. This study confirms the presence of anemia in 91% of patients with acute renal failure and shows it to be related to rise in urea and presence of oliguria. Clearly, however, the anemia is multifactorial, since in one-quarter of the patients it precedes onset of renal failure.Keywords
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