Genital porokeratosis: a series of 10 patients and review of the literature
- 8 May 2006
- journal article
- review article
- Published by Wiley in British Journal of Dermatology
- Vol. 155 (2), 325-329
- https://doi.org/10.1111/j.1365-2133.2006.07295.x
Abstract
Porokeratosis (PK) is an uncommon disorder of epidermal keratinization with a unique clinical appearance, unknown aetiology, and an unpredictable outcome. Genital PK (defined as localized PK confined to the genital area in this study) is extremely rare and is not well documented. To evaluate the clinical manifestations, histopathology, clinical course and treatment response for genital PK. We reviewed the clinicohistological data from 10 patients with genital PK seen at Chang Gung Memorial Hospital from 1990 to 2005. Seven patients had lesions only in the genital area, and three patients had genital and adjacent areas involved. All patients were male and the mean age at initial diagnosis was 46.0 years (range 36-59). All but one patient presented with pruritic lesions. Three patients (30%) had diabetes mellitus. No malignant transformation was observed. Surgical excision was the most effective treatment if it could be performed. Genital PK appeared more frequently in the Asian population than in reports from western countries. Genital PK presented mostly as pruritic lesions in Taiwan, with a wide age distribution. Long-term follow-up might be needed.Keywords
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