AFM Single Molecule Experiments at the Solid−Liquid Interface: In Situ Conformation of Adsorbed Flexible Polyelectrolyte Chains
- 25 October 2005
- journal article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 127 (45), 15688-15689
- https://doi.org/10.1021/ja0558239
Abstract
This paper reports the in situ study of conformations of flexible synthetic polymer molecules of protonated poly(2-vinylpyridine) at the solid-liquid interface at different pH of aqueous solutions. The direct conformation study of such thin ( approximately 0.4 nm) single molecules under liquid is performed for the first time. The highly protonated poly(2-vinylpyridine) chains possess a conformation of 2D equilibrated random coil, while at low degree of protonation, molecules are in the conformation of a strongly compressed 3D coil. Molecules are immobile during the few hours of the AFM experiment.Keywords
This publication has 14 references indexed in Scilit:
- Site-Specific Binding of the 9.5 Kilodalton DNA-Binding Protein ORF80 Visualized by Atomic Force MicroscopyBiomacromolecules, 2005
- Macromolecules at surfaces: Research challenges and opportunities from tribology to biologyJournal of Polymer Science Part B: Polymer Physics, 2003
- High Shape Persistence in Single Polymer Chains Rigidified with Lateral Hydrogen Bonded NetworksMacromolecules, 2002
- Adsorption of Hydrophobic Polyelectrolytes at Oppositely Charged SurfacesMacromolecules, 2002
- DNA on Fluid Membranes: A Model Polymer in Two DimensionsMacromolecules, 2000
- Adsorption of charged polymersJournal of Physics: Condensed Matter, 2000
- Strongly Charged, Flexible Polyelectrolytes in Poor Solvents: Molecular Dynamics SimulationsLangmuir, 1999
- Computer Simulation Studies of a Single Polyelectrolyte Chain in Poor SolventMacromolecules, 1999
- Cascade of Transitions of Polyelectrolytes in Poor SolventsMacromolecules, 1996
- X‐ray structure determination of isotactic poly(2‐vinylpyridine)Journal of Polymer Science: Polymer Physics Edition, 1977