Electroencephalographic Activation With Sleep and Methohexital
- 1 October 1972
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Neurology
- Vol. 27 (4), 361-363
- https://doi.org/10.1001/archneur.1972.00490160089013
Abstract
Two types of electroencephalographic activations were observed in 41 epileptics during sleep and intravenous administration of methohexital sodium. Type 1 was the induction of specific paroxysmal discharges (SPD) in an otherwise normal tracing; it occurred in four patients during sleep and in two patients during methohexital. Type 2 was an increase of 30% or more in the frequency of SPD in a preexisting abnormal tracing; it occurred in 20 patients during sleep and in 15 during methohexital administration. Type 1 activation improved the sensitivity of electroencephalography as a diagnostic tool by 10%. However, this was achieved mainly with sleep, because whenever methohexital elicited a type 1 response a similar activation had already been obtained during sleep. Methohexital activation shows no further effectiveness than sleep and had little value in the diagnosis of the epilepsies.Keywords
This publication has 2 references indexed in Scilit:
- Electroencephalographic activation with intravenous methohexital in psychomotor epilepsyNeurology, 1971
- The use of methohexitone in sleep electroencephalographyElectroencephalography and Clinical Neurophysiology, 1967