Identifying Nonproportional Covariates in the Cox Model
- 30 January 2008
- journal article
- survival analysis
- Published by Taylor & Francis Ltd in Communications in Statistics - Theory and Methods
- Vol. 37 (4), 617-625
- https://doi.org/10.1080/03610920701669744
Abstract
This paper addresses problem of testing whether an individual covariate in the Cox model has a proportional (i.e., time-constant) effect on the hazard. Two existing methods are considered: one is based on the component of the score process, and the other is a Neyman type smooth test. Simulations show that, when the model contains both proportional and nonproportional covariates, these methods are not reliable tools for discrimination. A simple yet effective solution is proposed based on smooth modeling of the effects of the covariates not in focus.Keywords
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