Targeting Transforming Growth Factor-Beta1 (TGF-β1) Inhibits Tumorigenesis of Anaplastic Thyroid Carcinoma Cells Through ERK1/2-NFκkB-PUMA Signaling
Open Access
- 30 June 2016
- journal article
- retracted article
- Published by International Scientific Information, Inc. in Medical Science Monitor
- Vol. 22, 2267-2277
- https://doi.org/10.12659/msm.898702
Abstract
BACKGROUND:The transforming growth factor-beta (TGF-β) signaling pathway plays a critical role in promoting tumor growth. TGF-β1was found to be overexpressed in anaplastic thyroid cancer (ATC). We therefore tested our hypothesis that targeting TGF-...Keywords
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