Penetration of Topically Applied Dexamethasone Alcohol Into Human Aqueous Humor
- 1 May 1988
- journal article
- research article
- Published by American Medical Association (AMA) in American Journal of Ophthalmology
- Vol. 106 (5), 686-687
- https://doi.org/10.1001/archopht.1988.01060130748037
Abstract
• Gas chromatography combined with mass spectrometry was used to determine the absorption of topically applied dexamethasone alcohol into the aqueous humor of human subjects undergoing routine intraocular surgery. The dexamethasone concentration in aqueous humor was greatest in the interval between 91 and 120 minutes following instillation (mean concentration, 31 ng/mL). Dexamethasone was still detectable in the aqueous 12 hours after instillation.This publication has 6 references indexed in Scilit:
- Penetration of timolol eye drops into human aqueous humour.British Journal of Ophthalmology, 1981
- Effect of Particle Size on Ophthalmic Bioavailability of Dexamethasone Suspensions in RabbitsJournal of Pharmaceutical Sciences, 1980
- Ocular Penetration in Rabbits of Topically Applied DexamethasoneAmerican Journal of Ophthalmology, 1974
- Ocular Absorption of Dexamethasone Phosphate Disodium by the RabbitAmerican Journal of Ophthalmology, 1967
- Ocular Penetration StudiesAmerican Journal of Ophthalmology, 1966
- Methyl- and Fluoro-Substituted Prednisolones in the Blood and Aqueous Humor of the RabbitA.M.A. Archives of Ophthalmology, 1960