Nucleus accumbens subregions: hodological and immunohistochemical study in the domestic chick (Gallus domesticus)
- 7 October 2006
- journal article
- Published by Springer Science and Business Media LLC in Cell and tissue research
- Vol. 327 (2), 221-230
- https://doi.org/10.1007/s00441-006-0295-0
Abstract
The nucleus accumbens was identified in avian species some time ago. However, the precise localization and extent of this nucleus is still a matter of controversy. We have used immunolabeling against calbindin, neuropeptide Y, and DARPP-32 (dopamine- and adenosine-related phosphoprotein, 32 kDa) for the selective marking of putative accumbens subdivisions and have followed the anterograde transport of biotinylated dextran amine injected to the nucleus tractus solitarii region of 7-day-old domestic chicks. The nucleus accumbens extending between rostrocaudal atlas coordinates A 10.6 and A 8.8 can be subdivided into the core and shell, the core corresponding to the ventromedial and juxtaventricular medial striatum laterodorsal to the bed nucleus of stria terminalis, and the shell representing an arched region situated ventrally and ventrolaterally to the core. Immunoreactivity to both calbindin and neuropeptide Y is more intense in the shell than in the core division. DARPP-32 immunolabeling does not differ in the two divisions but is markedly weaker in the bed nucleus of stria terminalis, enabling the separation of this nucleus from the surrounding accumbens subdivisions. Fibers from the nucleus solitarius predominantly terminate in the shell division, similar to the situation described in mammals. Whereas the suggested core lies entirely within the boundary of the medial striatum, the shell seems partially to overlap the ventral pallidum. We have been unable to subdivide the remaining part of accumbens lying rostral to A 10.6 into a putative shell and core by the methods employed in the present study. This region probably corresponds to the rostral pole of the nucleus accumbens.Keywords
This publication has 44 references indexed in Scilit:
- Localized lesions of ventral striatum, but not arcopallium, enhanced impulsiveness in choices based on anticipated spatial proximity of food rewards in domestic chicksBehavioural Brain Research, 2006
- Neural correlates of the proximity and quantity of anticipated food rewards in the ventral striatum of domestic chicksEuropean Journal of Neuroscience, 2005
- Evidence for “direct” and “indirect” pathways through the song system basal gangliaJournal of Comparative Neurology, 2005
- Behavioural consequences of nucleus accumbens dopaminergic stimulation and glutamatergic blocking in pigeonsBehavioural Brain Research, 2002
- Intratelencephalic connections of the hippocampus in pigeons (Columba livia)Journal of Comparative Neurology, 2002
- Selective striatal connections of midbrain dopaminergic nuclei in the chick ( Gallus domesticus )Cell and tissue research, 2002
- Structural and functional evolution of the basal ganglia in vertebratesBrain Research Reviews, 1998
- Projections of the nucleus of the tractus solitarius in the pigeon (Columba livia)Journal of Comparative Neurology, 1988
- Catecholaminergic innervation of the septal area in man: Immunocytochemical study using TH and DBH antibodiesJournal of Comparative Neurology, 1985
- The central adrenergic system. An immunofluorescence study of the location of cell bodies and their efferent connections in the rat utilizing dopamine‐B‐hydroxylase as a markerJournal of Comparative Neurology, 1975