Continuous-wave laser generated jets for needle free applications

Abstract
We designed and built a microfluidic device for the generation of liquid jets produced by thermocavitation. A continuous wave (CW) laser was focused inside a micro-chamber filled with a light-absorbing solution to create a rapidly expanding vapor bubble. The chamber is connected to a micro-channel which focuses and ejects the liquid jet through the exit. The bubble growth and the jet velocity were measured as a function of the devices geometry (channel diameter D and chamber width A). The fastest jets were those for relatively large chamber size with respect to the channel diameter. Elongated and focused jets up to 29 m/s for a channel diameter of 250 μm and chamber size of 700 μm were obtained. The proposed CW laser-based device is potentially a compact option for a practical and commercially feasible needle-free injector.
Funding Information
  • Consejo Nacional de Ciencia y Tecnología