Core–Shell Pd@Au Nanoplates as Theranostic Agents for In‐Vivo Photoacoustic Imaging, CT Imaging, and Photothermal Therapy
Top Cited Papers
- 31 October 2014
- journal article
- research article
- Published by Wiley in Advanced Materials
- Vol. 26 (48), 8210-8216
- https://doi.org/10.1002/adma.201404013
Abstract
Uniform plasmonic Pd@Au core–shell bimetallic nanoplates are synthesized by seeded growth strategy. Surface modified with SH-PEG makes it good biocompatibility, prolonged blood circulation, and relatively high tumor accumulation. Enhanced tumor contrast effects can be obtained for in vivo photoacoustic/CT imaging after intravenous injection of Pd@Au-PEG. Moreover, efficient photothermal tumor ablation is achieved, guided by the imaging techniques. This work promises further exploration of the superiority of 2D nanostructures for in vivo biomedical applications.Keywords
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