Drug‐resistant mutants of chinese hamster ovary cells possess an altered cell surface carbohydrate component

Abstract
Surface label experiments using the galactose oxidase‐[3 H] ‐borohydride technique reveal that cells from drug‐resistant Chinese hamster ovary clones possess a surface carbohydrate component of apparent molecular weight 165,000 which is absent from wild‐type cells. The component may also be demonstrated by [14C] glucosamine incorporation but not by [3 H] leucine incorporation or by the lactoperoxidase surface labeling reaction.