Materials and Manufacturing Technologies Available for Production of a Pediatric Bioabsorbable Stent
Open Access
- 8 September 2013
- journal article
- review article
- Published by Hindawi Limited in BioMed Research International
- Vol. 2013, 1-11
- https://doi.org/10.1155/2013/137985
Abstract
Transcatheter treatment of children with congenital heart disease such as coarctation of the aorta and pulmonary artery stenosis currently involves the use of metal stents. While these provide good short term results, there are long term complications with their use. Children outgrow metal stents, obligating them to future transcatheter dilations and eventual surgical removal. A bioabsorbable stent, or a stent that goes away with time, would solve this problem. Bioabsorbable stents are being developed for use in coronary arteries, however these are too small for use in pediatric congenital heart disease. A bioabsorbable stent for use in pediatric congenital heart disease needs to be low profile, expandable to a diameter 8 mm, provide sufficient radial strength, and absorb quickly enough to allow vessel growth. Development of absorbable coronary stents has led to a great understanding of the available production techniques and materials such as bioabsorbable polymers and biocorrodable metals. Children with congenital heart disease will hopefully soon benefit from the current generation of bioabsorbable and biocorrodable materials and devices.Keywords
This publication has 47 references indexed in Scilit:
- Absorbable stent: focus on clinical applications and benefitsVascular Health and Risk Management, 2012
- Comparison of Surgical, Stent, and Balloon Angioplasty Treatment of Native Coarctation of the Aorta: An Observational Study by the CCISC (Congenital Cardiovascular Interventional Study Consortium)Journal of the American College of Cardiology, 2011
- Magnesium used in bioabsorbable stents controls smooth muscle cell proliferation and stimulates endothelial cells in vitroJournal of Biomedical Materials Research Part B: Applied Biomaterials, 2011
- From metallic cages to transient bioresorbable scaffolds: change in paradigm of coronary revascularization in the upcoming decade?European Heart Journal, 2011
- Chronic magnesium deficiency decreases tolerance to hypoxia/reoxygenation injury in mouse heartLife Sciences, 2011
- Clinical Use of Intravenous Iron: Administration, Efficacy, and SafetyHematology-American Society Hematology Education Program, 2010
- Fabrication of Balloon-Expandable Self-Lock Drug-Eluting Polycaprolactone Stents Using Micro-Injection Molding and Spray Coating TechniquesAnnals of Biomedical Engineering, 2010
- Bioabsorbable Coronary StentsCirculation: Cardiovascular Interventions, 2009
- Grain structure of thin electrodeposited and rolled copper foilsMaterials Characterization, 2004
- Syndromic paucity of interlobular bile ducts (Alagille syndrome or arteriohepatic dysplasia): Review of 80 casesThe Journal of Pediatrics, 1987