Reproducibility of Computer-Aided Volumetry of Artificial Small Pulmonary Nodules in Ex Vivo Porcine Lungs
- 1 January 2006
- journal article
- Published by Ovid Technologies (Wolters Kluwer Health) in Investigative Radiology
- Vol. 41 (1), 28-35
- https://doi.org/10.1097/01.rli.0000191366.05586.4d
Abstract
The main purpose of this study was to investigate the reproducibility of computed tomography (CT)-based volumetric measurements of small pulmonary nodules. We implanted 70 artificial pulmonary nodules in 5 ex vivo porcine lungs in a dedicated chest phantom. The lungs were scanned 5 times consecutively with multislice-CT (collimation 16 x 0.75 mm, slice thickness 1 mm, reconstruction increment 0.7 mm). A commercial software package was used for lesion volumetry. The authors differentiated between intrascan reproducibility, interscan reproducibility, and results from semiautomatic and postprocessed volumetry. Analysis of intrascan reproducibility revealed a mean variation coefficient of 6.2% for semiautomatic volumetry and of 0.7% for human adapted volumetry. For interscan reproducibility a mean variation coefficient of 9.2% and for human adapted volumetry a mean of 3.7% was detected. The presented volumetry software showed a high reproducibility that can be expected to detect nodule growth with a high degree of certainty.Keywords
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