Investigating the relationship between hyposalivation and mucosal wetness
- 28 October 2010
- journal article
- research article
- Published by Wiley in Oral Diseases
- Vol. 17 (1), 109-114
- https://doi.org/10.1111/j.1601-0825.2010.01715.x
Abstract
Background: Mucosal wetness (MW) reflects the layer of residual saliva that covers the oral mucosal surfaces. Objectives: The aim of this study was to determine MW at different oral mucosa sites and to investigate the relationship between MW, unstimulated whole salivary flow rates (UWS) and Clinical Oral Dryness Score (CODS). Method: A total of 100 dry mouth patients and 50 healthy subjects participated in the study. MW was sampled with filter paper strips at four sites inside the mouth; anterior hard palate (AHP), buccal mucosa (BUC), anterior tongue (AT), lower lip (LL) and measured with a micro-moisture meter. Reproducibility was assessed by repeated sampling and diurnal variation was examined. Results: Mucosal wetness in healthy subjects differed according to site and means +/- SD were; AHP (11 +/- 11.7 mu m), BUC (32 +/- 14.8 mu m), AT (65 +/- 17.2 mu m), and LL (25 +/- 13.5 mu m). Dry mouth patients with reduced UWS showed increased CODS. MW at all four sites was significantly reduced (P < 0.05) in dry mouth patients compared with the healthy subjects. Reproducibility of MW measurement using the intra-class correlation coefficient showed agreement at different visits within subject. MW of the AT showed a positive correlation with UWS (P < 0.05). Conclusion: Mucosal wetness is a reliable measure of oral dryness and had a positive correlation with UWS.This publication has 28 references indexed in Scilit:
- Reduced sulfation of muc5b is linked to xerostomia in patients with Sjogren syndromeAnnals Of The Rheumatic Diseases, 2008
- Salivary gland parameters and clinical data related to the underlying disorder in patients with persisting xerostomiaEuropean Journal of Oral Sciences, 2007
- Oral Dryness Examinations : Use of an Oral Moisture Checking Device and a Modified Cotton MethodProsthodontic Research & Practice, 2006
- Salivary Hypofunction and Xerostomia: Diagnosis and TreatmentDental Clinics of North America, 2005
- Minor gland saliva flow rate and proteins in subjects with hyposalivation due to Sjögren's syndrome and radiation therapyArchives of Oral Biology, 2005
- Drug effects on salivary glands: dry mouthOral Diseases, 2003
- Relationship of medical status, medications, and salivary flow rates in adults of different agesOral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 1996
- A Method for Measuring the Flow of Saliva from the Minor Salivary GlandsJournal of Dental Research, 1990
- The Surface Area of the Adult Human Mouth and Thickness of the Salivary Film Covering the Teeth and Oral MucosaJournal of Dental Research, 1987
- Xerostomia in the Elderly: Prevalence, Diagnosis, Complications and Treatment1Gerodontology, 1985