A Comparison of Budesonide with Prednisolone for Active Crohn's Disease
- 29 September 1994
- journal article
- clinical trial
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 331 (13), 842-845
- https://doi.org/10.1056/nejm199409293311304
Abstract
Patients with active Crohn's disease are often treated with corticosteroids, but the treatment has many side effects. Budesonide is a potent, well-absorbed corticosteroid, but because of a high rate of first-pass metabolism in the liver, its systemic bioavailability is low.Keywords
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