An NAADP-gated Two-pore Channel Targeted to the Plasma Membrane Uncouples Triggering from Amplifying Ca2+ Signals
Open Access
- 1 December 2010
- journal article
- Published by Elsevier BV
- Vol. 285 (49), 38511-38516
- https://doi.org/10.1074/jbc.m110.162073
Abstract
No abstract availableThis publication has 34 references indexed in Scilit:
- Characterization of Two-pore Channel 2 (TPCN2)-mediated Ca2+ Currents in Isolated LysosomesPublished by Elsevier BV ,2010
- Two-pore channels: Regulation by NAADP and customized roles in triggering calcium signalsCell Calcium, 2010
- Acidic calcium stores open for business: expanding the potential for intracellular Ca2+ signalingTrends in Cell Biology, 2010
- Purified TPC Isoforms Form NAADP Receptors with Distinct Roles for Ca2+ Signaling and Endolysosomal TraffickingCurrent Biology, 2010
- An Ancestral Deuterostome Family of Two-pore Channels Mediates Nicotinic Acid Adenine Dinucleotide Phosphate-dependent Calcium Release from Acidic Organelles*Published by Elsevier BV ,2010
- NAADP-mediated Ca 2+ signaling via type 1 ryanodine receptor in T cells revealed by a synthetic NAADP antagonistProceedings of the National Academy of Sciences of the United States of America, 2009
- The two-pore channel TPCN2 mediates NAADP-dependent Ca2+-release from lysosomal storesPflügers Archiv - European Journal of Physiology, 2009
- NAADP mobilizes calcium from acidic organelles through two-pore channelsNature, 2009
- Clustering of InsP3 receptors by InsP3 retunes their regulation by InsP3 and Ca2+Nature, 2009
- Identification of a chemical probe for NAADP by virtual screeningNature Chemical Biology, 2009