Frequency of Daytime Biochemical Hypoglycaemia in Insulin‐treated Diabetic Patients: Relation to Daily Median Blood Glucose Concentrations
- 1 March 1986
- journal article
- research article
- Published by Wiley in Diabetic Medicine
- Vol. 3 (2), 147-151
- https://doi.org/10.1111/j.1464-5491.1986.tb00726.x
Abstract
The frequency and distribution of daytime biochemical hypoglycaemia (capillary blood glucose concentration below 3 mmol/l) was assessed in type 1 diabetic patients on conventional twice daily insulin therapy (n = 79) and on continuous subcutaneous insulin infusion (n = 20). Patients collected and mailed to the hospital blood for seven-point blood glucose profiles. For both treatment regimens the frequency of biochemical hypoglycaemia on individual days was inversely related to the median blood glucose concentration in a curvilinear manner (p less than 0.001). Hypoglycaemia was more frequent pre-prandially than post-prandially (p less than 0.01), and was evenly distributed during the day in patients on continuous subcutaneous insulin infusion. In patients on conventional therapy, however, pre-lunch hypoglycaemia was four times more frequent than pre-breakfast or pre-dinner hypoglycaemia (p less than 0.0001).Keywords
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