ABO blood group and secretor status in relation to clinical characteristics of peptic ulcers

Abstract

Prognosis for peptic ulcer appears to be influenced by the ABO blood group and the ABH secretor status (ability to secrete blood group substances in mucus). Group O patients are more likely to suffer from bleeding than are those of other blood groups, but are not particularly likely to come to operation. Non-secretors are not prone to suffer from bleeding but tend to come to operation more often. This dissociated effect has not been explained, although normal persons of group O are known to have slightly lower plasma levels of factor VIII, antihemophilic globulin, than do those of group A.