Incidence, Types, Risk Factors, and Outcome of Stroke in a Developing Country
- 1 April 2009
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Stroke
- Vol. 40 (4), 1212-1218
- https://doi.org/10.1161/strokeaha.108.531293
Abstract
Background and Purpose— Despite increasing burden of stroke in developing countries, population-based data are rare. Through the Trivandrum Stroke Registry, we intend to assess incidence, types, risk factors, and outcome of stroke among urban and rural dwellers of a South Indian community. Methods— We ascertained all first-ever strokes occurring among 741 000 urban and 185 000 rural inhabitants of Trivandrum, Kerala. In addition to Steps 1 and 2 of World Health Organization STEPS Stroke Manual, we used multiple supplementary methods to maximize ascertainment of nonfatal and nonhospitalized fatal stroke events in the community. Results— During a 6-month period, 541 strokes were registered, 431 in the urban and 110 in the rural communities. Stroke occurred at a median age of 67 years; only 3.8% of patients were aged ≤40 years. Adjusted annual incidence rates per 100 000 were 135 (95% confidence interval 123 to 146) for total, 135 (122–148) for urban, and 138 (112–164) for rural populations, and 74.8 (66.3 to 83.2), 10.1 (7.0 to 13.2), and 4.2 (2.2 to 6.1) for ischemic stroke, intracerebral hemorrhage, and subarachnoid hemorrhage, respectively. There was more stroke of undetermined type in the rural community. One or more modifiable risk factors were identified in 90% patients. More rural male patients smoked tobacco. The 28th day case fatality rate was 24.5% for urban and 37.1% for rural populations ( P =0.011). Conclusions— There are more similarities than differences between developing and developed countries in the epidemiology of stroke. Compared to urban stroke patients, rural ones are less likely to be optimally investigated and treated.This publication has 19 references indexed in Scilit:
- Disparity and Its Time Trends in Stroke Mortality Between Urban and Rural Populations in China 1987 to 2001Stroke, 2007
- Risk factors for acute ischaemic stroke in young adults in South IndiaJournal of Neurology, Neurosurgery & Psychiatry, 2007
- A Prospective Community-Based Study of Stroke in Kolkata, IndiaStroke, 2007
- Stroke and Thrombolysis in Developing CountriesInternational Journal of Stroke, 2007
- Burden of Stroke: Indian PerspectiveInternational Journal of Stroke, 2006
- Acute Ischemic Stroke Care and Outcome in Centers Participating in the Polish National Stroke Prevention and Treatment RegistryStroke, 2006
- Direct Assessment of Completeness of Ascertainment in a Stroke Incidence StudyStroke, 2004
- Prospective Community-Based Study of Stroke in Northern PortugalStroke, 2004
- Mortality and Recovery After Stroke in The GambiaStroke, 2003
- Stroke in the young: incidence and pattern in Benghazi, LibyaActa Neurologica Scandinavica, 1986