The total cellularity of the bone marrow in man
- 1 May 1962
- journal article
- research article
- Published by BMJ in Journal of Clinical Pathology
- Vol. 15 (3), 254-259
- https://doi.org/10.1136/jcp.15.3.254
Abstract
The Fe59 method of Suit (1957) has been used to estimate total bone marrow cellularity in 10 haematologically normal patients. A mean figure of 10·4 × 109 nucleated cells/kg. body weight was obtained. Simultaneous estimates from marrow obtained by rib excision produced a mean value of 11·1 × 109 nucleated cells/kg. Previous work by this and other methods is reviewed. While some results agree well with those of the present work, one is higher by 50% and another by 300%. Corrections are suggested which reduce these figures and bring all published results within a small range. Reasonably accurate determinations of total marrow cellularity in disease will not be possible until more is known of marrow Fe59 uptake in abnormal states.Keywords
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