SelectiveO-Benzylation of Aminoalkanols
- 1 March 1995
- journal article
- research article
- Published by Taylor & Francis Ltd in Synthetic Communications
- Vol. 25 (6), 907-913
- https://doi.org/10.1080/00397919508013428
Abstract
A simple and one-step method has been developed for selective O-benzylation of aminoalkanols. Study of steric effects shows the best selectivity in adjacent 1°-OH vs 2°-CHNH2 and decreased selectivity in 2°-OH vs 1°-CH2NH2 and non adjacen aminoalkanol.Keywords
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