Characteristic and Synthetic Approach of Molecularly Imprinted Polymer
Open Access
- 28 June 2006
- journal article
- research article
- Published by MDPI AG in International Journal of Molecular Sciences
- Vol. 7 (5), 155-178
- https://doi.org/10.3390/i7050155
Abstract
Molecularly imprinted polymers (MIP) exhibiting high selectivity and affinity tothe predetermined molecule (template) are now seeing a fast growing research. However,optimization of the imprinted products is difficult due to the fact that there are manyvariables to consider, some or all of which can potentially impact upon the chemical,morphological and molecular recognition properties of the imprinted materials. This reviewpresent a summary of the principal synthetic considerations pertaining to good practice in thepolymerization aspects of molecular imprinting, and is primarily aimed at researcher familiarwith molecular imprinting methods but with little or no prior experience in polymersynthesis. The synthesis, characteristic, effect of molecular recognition and differentpreparation methods of MIP in recent few years are discussed in this review, unsolvedproblems and possible developments of MIP were also been briefly discussed.This publication has 102 references indexed in Scilit:
- Rapid and efficient chiral separation of nateglinide and its l-enantiomer on monolithic molecularly imprinted polymersJournal of Chromatography A, 2005
- Preparation of a sensor device with specific recognition sites for acetaldehyde by molecular imprinting techniqueSensors and Actuators B: Chemical, 2002
- Molecularly Imprinted Polymers and Their Use in Biomimetic SensorsChemical Reviews, 2000
- Molecular imprints as artificial antibodies — a new generation of chemical sensorsSensors and Actuators B: Chemical, 2000
- Molecular imprinting for bio- and pharmaceutical analysisTrAC Trends in Analytical Chemistry, 1999
- Synthesis of molecular imprinted polymer networksChromatographia, 1998
- Molecularly imprinted polymers for bioanalysis: chromatography, binding assays and biomimetic sensorsCurrent Opinion in Biotechnology, 1996
- Drug assay using antibody mimics made by molecular imprintingNature, 1993
- On the control of microenvironment shape of functionalized network polymers prepared by template polymerizationJournal of the American Chemical Society, 1989
- The Preparation of Specific AdsorbentsProceedings of the National Academy of Sciences of the United States of America, 1949