Human UDP-Glucuronosyltransferases: Metabolism, Expression, and Disease
Top Cited Papers
- 1 April 2000
- journal article
- review article
- Published by Annual Reviews in Annual Review of Pharmacology and Toxicology
- Vol. 40 (1), 581-616
- https://doi.org/10.1146/annurev.pharmtox.40.1.581
Abstract
In vertebrates, the glucuronidation of small lipophilic agents is catalyzed by the endoplasmic reticulum UDP-glucuronosyltransferases (UGTs). This metabolic pathway leads to the formation of water-...Keywords
This publication has 130 references indexed in Scilit:
- Isolation and Characterization of a Human Orphan UDP-Glucuronosyltransferase, UGT2B11Biochemical and Biophysical Research Communications, 1998
- Characterization of Two UDP Glucuronosyltransferases That Are Predominantly Expressed in Human ColonBiochemical and Biophysical Research Communications, 1998
- cDNA Cloning and Characterization of the Human UDP Glucuronosyltransferase, UGT1A3Biochemical and Biophysical Research Communications, 1996
- Identification of Defect in the Genes for Bilirubin UDP-Glucuronosyltransferase in a Patient with Crigler-Najjar Syndrome Type IIBiochemical and Biophysical Research Communications, 1993
- Characterization of a cloned human dihydrotestosterone/androstanediol UDP-glucuronosyltransferase and its comparison to other steroid isoformsBiochemistry, 1993
- cDNA Cloning and Expression of Two New Members of the Human Liver UDP-Glucuronosyltransferase 2B SubfamilyBiochemical and Biophysical Research Communications, 1993
- Isolation, Sequence, and Developmental Expression of RatUGT2B2: The Gene Encoding a Constitutive UDP Glucuronosyltransferase That Metabolizes Etiocholanolone and AndrosteroneDNA and Cell Biology, 1991
- Anti-liver kidney microsome antibody type 1 recognizes human cytochrome P450 db1Biochemical and Biophysical Research Communications, 1989
- Cloning of cDNAs coding for rat hepatic microsomal UDP-glucuronyltransferasesGene, 1985
- Cleavage of nascent UDP glucuronosyltransferase from rat liver by dog pancreatic microsomesBiochemical and Biophysical Research Communications, 1984