The cortical topography of human swallowing musculature in health and disease
- 1 November 1996
- journal article
- Published by Springer Science and Business Media LLC in Nature Medicine
- Vol. 2 (11), 1217-1224
- https://doi.org/10.1038/nm1196-1217
Abstract
Because no detailed information exists regarding the topographic representation of swallowing musculature on the human cerebral cortex in health or disease, we used transcranial magnetic stimulation to study the cortical topography of human oral, pharyngeal and esophageal musculature in 20 healthy individuals and the topography of pharyngeal musculature in two stroke patients, one with and one without dysphagia. Our results demonstrate that swallowing musculature is discretely and somatotopically represented on the motor and premotor cortex of both hemispheres but displays interhemispheric asymmetry, independent of handedness. Following stroke, dysphagia appeared to be associated with smaller pharyngeal representation on the intact hemisphere, which increases in size with recovery of swallowing.Keywords
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