Sugar‐Responsive Fluorescent Nanospheres
- 11 February 2008
- journal article
- research article
- Published by Wiley in Macromolecular Bioscience
- Vol. 8 (2), 146-152
- https://doi.org/10.1002/mabi.200700174
Abstract
Sugar-responsive polymer fluorescent nanospheres based on N-isopropylacrylamide and phenylboronic acid were prepared by precipitation polymerization with an average size of 380 nm. The particles swell in the presence of sugar, and the rate and extent of this swelling was measured with distance-dependent fluorescence resonance energy transfer. We present a direct link between the ratio of the intensities of the fluorophores and the particle size. Depending on the kind of sugar and the sugar concentration, different swelling kinetics and equilibrium sizes are observed. With this approach we can obtain insight into complex structure changes with simple fluorescent measurements.This publication has 22 references indexed in Scilit:
- Engineering Glucose Swelling Responses in Poly(N-isopropylacrylamide)-Based MicrogelsMacromolecules, 2007
- Monodispersed Glucose-Responsive Microgels Operating at Physiological SalinityBiomacromolecules, 2006
- Synthesis and Volume Phase Transitions of Glucose-Sensitive MicrogelsBiomacromolecules, 2006
- Transduction of Volume Change in pH‐Sensitive Hydrogels with Resonance Energy TransferAdvanced Materials, 2006
- A Chemomechanical Polymer that Functions in Blood Plasma with High Glucose SelectivityAngewandte Chemie-International Edition, 2006
- Effects of Polyols, Saccharides, and Glycoproteins on Thermoprecipitation of Phenylboronate-Containing CopolymersBiomacromolecules, 2006
- Glucose-Responsive Polymer Gel Bearing Phenylborate Derivative as a Glucose-Sensing Moiety Operating at the Physiological pHBiomacromolecules, 2004
- Swelling and Shrinking Kinetics of Totally Synthetic, Glucose-Responsive Polymer Gel Bearing Phenylborate Derivative as a Glucose-Sensing MoietyMacromolecules, 2004
- Totally Synthetic Polymer Gels Responding to External Glucose Concentration: Their Preparation and Application to On−Off Regulation of Insulin ReleaseJournal of the American Chemical Society, 1998
- Simultaneous monitoring of pH, CO2 and O2 using an optical imaging fiberAnalytica Chimica Acta, 1997