Macula densa signalling—a potential role of cyclooxygenase‐2 (COX‐2)?
Open Access
- 1 October 2000
- journal article
- research article
- Published by Oxford University Press (OUP) in Nephrology Dialysis Transplantation
- Vol. 15 (10), 1504-1506
- https://doi.org/10.1093/ndt/15.10.1504
Abstract
Prostaglandins are mediators of vascular tone and salt and water homeostasis in the mammalian kidney; their regulation of glomerular haemodynamics and distal nephron function has been well described. Renin production and release is also known to be mediated by prostaglandins generated by afferent arteriole and by prostaglandin‐dependent signalling from the macula densa [1].Keywords
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