Changes of Serum 3-Methylhistidine Concentration and Energy-Associated Metabolites in Dairy Cows with Ketosis
Open Access
- 1 January 2007
- journal article
- Published by Japanese Society of Veterinary Science in The Journal of Veterinary Medical Science
- Vol. 69 (10), 1091-1093
- https://doi.org/10.1292/jvms.69.1091
Abstract
The present study examined the Serum 3-methylhistidine concentrations and energy-associated variables of 5 healthy Holstein cows and 5 Holstein cows with ketosis. The serum total cholesterol and apolipoprotein B-100 concentrations and lecithin-cholesterol acyltransferase (LCAT) activity of the ketotic cows were lower than those of the healthy cows 14 days before parturition. The serum non-esterified fatty acid (NEFA) concentration on the day of parturition and 3-methylhistidine concentration 14 days after parturition were higher in the ketotic cows. The serum 3-methylhistidine concentration 14 days after parturition was negatively correlated with the serum LCAT activity 14 days before parturition and was positively correlated with the serum NEFA concentration on the day of parturition. Insufficiency of cholesterol metabolism and acceleration of body fat degradation occur before parturition in cows with ketosis, and these characteristics are correlated with acceleration of protein degradation after parturition.Keywords
This publication has 12 references indexed in Scilit:
- Effects of high ambient temperature and restricted feed intake on urinary and plasma 3‐methylhistidine in lactating Holstein cowsAnimal Science Journal, 2006
- Effects of Fasting and Refeeding on Expression of Proteolytic-Related Genes in Skeletal Muscle of ChicksJournal of Nutritional Science and Vitaminology, 2005
- Peripartum Performance and Metabolism of Dairy Cows in Response to Prepartum Energy and Protein IntakeJournal of Dairy Science, 2002
- The Metabolic Profile Test: Its Practicability in Assessing Feeding Management and Periparturient Diseases in High Yielding Commercial Dairy Herds.The Journal of Veterinary Medical Science, 2002
- Reduction in Serum Lecithin:Cholesterol Acyltransferase Activity Prior to the Occurrence of Ketosis and Milk Fever in Cows.The Journal of Veterinary Medical Science, 2000
- Physiological Changes at Parturition and Their Relationship to Metabolic DisordersJournal of Dairy Science, 1997
- PlasmaNτ-Methylhistidine Concentration Is a Sensitive Index of Myofibrillar Protein Degradation during Starvation in RatsBioscience, Biotechnology, and Biochemistry, 1996
- Effect of Starvation on the PlasmaNτ-Methylhistidine Concentration in GoatsBioscience, Biotechnology, and Biochemistry, 1993
- 3-Methylhistidine as a Measure of Skeletal Muscle Protein Breakdown in Human Subjects: The Case for Its Continued UseClinical Science, 1983
- Fat Cow SyndromeJournal of Dairy Science, 1976