Mucosal Imprinting of Vaccine-Induced CD8 + T Cells Is Crucial to Inhibit the Growth of Mucosal Tumors
- 13 February 2013
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science Translational Medicine
- Vol. 5 (172), 172ra20
- https://doi.org/10.1126/scitranslmed.3004888
Abstract
Mucosal vaccination induces targeted CD8 + T cell homing to inhibit mucosal tumors.Keywords
This publication has 54 references indexed in Scilit:
- Sublingual Immunization with Nonreplicating Antigens Induces Antibody-Forming Cells and Cytotoxic T Cells in the Female Genital Tract Mucosa and Protects against Genital Papillomavirus InfectionThe Journal of Immunology, 2009
- What Role Does the Route of Immunization Play in the Generation of Protective Immunity against Mucosal Pathogens?The Journal of Immunology, 2009
- Vaccination against HPV-16 Oncoproteins for Vulvar Intraepithelial NeoplasiaThe New England Journal of Medicine, 2009
- Tumor antigen–specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impairedBlood, 2009
- Identification of a dendritic cell receptor that couples sensing of necrosis to immunityNature, 2009
- Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challengeNature Medicine, 2009
- Intrarectal Vaccination with Recombinant Vaccinia Virus Expressing Carcinoembronic Antigen Induces Mucosal and Systemic Immunity and Prevents Progression of Colorectal CancerThe Journal of Immunology, 2008
- Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeysNature, 2008
- Trafficking of Antigen-Specific CD8+ T Lymphocytes to Mucosal Surfaces following Intramuscular VaccinationThe Journal of Immunology, 2008
- The microbial mimic poly IC induces durable and protective CD4+T cell immunity together with a dendritic cell targeted vaccineProceedings of the National Academy of Sciences of the United States of America, 2008