Utilization of an In Vivo Reporter for High Throughput Identification of Branched Small Molecule Regulators of Hypoxic Adaptation
- 23 April 2010
- journal article
- Published by Elsevier BV in Cell Chemical Biology
- Vol. 17 (4), 380-391
- https://doi.org/10.1016/j.chembiol.2010.03.008
Abstract
No abstract availableKeywords
This publication has 52 references indexed in Scilit:
- Structural Basis for Binding of Hypoxia-Inducible Factor to the Oxygen-Sensing Prolyl HydroxylasesStructure, 2009
- Antioxidants, HIF Prolyl Hydroxylase Inhibitors or Short Interfering RNAs to BNIP3 or PUMA, Can Prevent Prodeath Effects of the Transcriptional Activator, HIF-1α, in a Mouse Hippocampal Neuronal LineAntioxidants and Redox Signaling, 2008
- Rapid Restoration of Cognition in Alzheimer's Transgenic Mice with 8-Hydroxy Quinoline Analogs Is Associated with Decreased Interstitial AβNeuron, 2008
- Neuron-Specific Inactivation of the Hypoxia Inducible Factor 1 Increases Brain Injury in a Mouse Model of Transient Focal Cerebral IschemiaJournal of Neuroscience, 2007
- Clioquinol, a Cu(II)/Zn(II) Chelator, Inhibits Both Ubiquitination and Asparagine Hydroxylation of Hypoxia-inducible Factor-1α, Leading to Expression of Vascular Endothelial Growth Factor and Erythropoietin in Normoxic CellsOnline Journal of Public Health Informatics, 2006
- A fluorescence polarization-based interaction assay for hypoxia-inducible factor prolyl hydroxylasesBiochemical and Biophysical Research Communications, 2005
- Coordinate Regulation of the Oxygen-Dependent Degradation Domains of Hypoxia-Inducible Factor 1αMolecular and Cellular Biology, 2005
- Stimulation of HIF-1α, HIF-2α, and VEGF by prolyl 4-hydroxylase inhibition in human lung endothelial and epithelial cellsFree Radical Biology & Medicine, 2005
- A Conserved Family of Prolyl-4-Hydroxylases That Modify HIFScience, 2001
- CHARMM: A program for macromolecular energy, minimization, and dynamics calculationsJournal of Computational Chemistry, 1983