Permeability of the Blood-Brain Barrier in the Rat after Local Proton Irradiation
- 1 January 1982
- journal article
- research article
- Published by Taylor & Francis Ltd in Acta Radiologica: Oncology
- Vol. 21 (4), 267-271
- https://doi.org/10.3109/02841868209134015
Abstract
Rats were irradiated laterally through the brain with 200 MeV protons. The beam was of circular cross-section with a diameter of 5 or 7 mm. The doses were 50, 70, 100 and 150 Gy. After irradiation the rats were examined several times by use of injected 99Tcm-pertechnetate. The uptake of the substance increased to a maximum after 20 to 30 days and then decreased to a normal level. Differences in maximum uptake with respect to dose were significant only for the smaller beam diameter.Keywords
This publication has 5 references indexed in Scilit:
- Ultrastructural basis for different pertechnetate uptake patterns by various human brain tumours.Journal of Neurology, Neurosurgery & Psychiatry, 1979
- A STUDY OF GLYCOLYTIC AND PENTOSE PHOSPHATE SHUNT ENZYMES IN RELATIONSHIP TO THE ALTERED PERMEABILITY IN THE BLOOD‐BRAIN BARRIERJournal of Neurochemistry, 1976
- The nature of latent cerebral irradiation damage and its modification by hypertensionThe British Journal of Radiology, 1970
- Microangiographic Studies on Changes in the Cerebral Vessels After Irradiation: II. Proton beam lesions in the ratActa Radiologica: Therapy, Physics, Biology, 1966
- Relation between Field Size and Tolerance of Rabbit's Brain to Roentgen Irradiation (200 kV) via a Slit-Shaped FieldActa Radiologica: Therapy, Physics, Biology, 1963