Slow Recovery from Critical Coronavirus Disease 2019 Pneumonia in an Immunosuppressed Renal Transplant Recipient with Early Acute Cardiorenal Syndrome
Open Access
- 1 December 2020
- journal article
- research article
- Published by S. Karger AG in Cardiorenal Medicine
- Vol. 10 (6), 470-475
- https://doi.org/10.1159/000510916
Abstract
With the global spread of SARS-Cov-2 infections, increasing numbers of COVID-19 cases have been reported in transplant recipients. However, reports are lacking concerning the treatment and prognosis of COVID-19 pneumonia in renal transplant recipients with acute cardiorenal syndrome. We report here the complete clinical course of a renal transplant recipient with critical COVID-19 pneumonia. In the early phase of SARS-Cov-2 infection, the patient exhibited extensive lung lesions and significant acute kidney and heart injuries, which required treatment in the ICU. After correcting the arrhythmia and heart failure, the patient recovered quickly from the acute kidney injury with a treatment of intensive diuresis and strict control of fluid intake. Without cessation of oral immunosuppressive agents, the patient presented a delayed and low antibody response against SARS-Cov-2 and reappeared positive for the virus twice after being discharged. Nevertheless, the patient's pneumonia continued to improve and he fully recovered in 69 days. This effectively treated case may be meaningful and referable for the treatment of COVID-19 pneumonia in other transplant recipients with acute cardiorenal syndrome.Keywords
This publication has 9 references indexed in Scilit:
- Distinguishing pancreatic cancer and autoimmune pancreatitis with in vivo tomoelastographyEuropean Radiology, 2020
- Covid-19 and Kidney TransplantationNew England Journal of Medicine, 2020
- Positive RT-PCR Test Results in Patients Recovered From COVID-19JAMA, 2020
- Acute kidney injury in SARS-CoV-2 infected patientsCritical Care, 2020
- Diagnostic value and dynamic variance of serum antibody in coronavirus disease 2019International Journal of Infectious Diseases, 2020
- Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort studyThe Lancet, 2020
- Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational studyThe Lancet Respiratory Medicine, 2020
- CRISPR-Cas14 is now part of the artillery for gene editing and molecular diagnosticNanomedicine: Nanotechnology, Biology and Medicine, 2019
- Special Issue: KDIGO Clinical Practice Guideline for the Care of Kidney Transplant RecipientsAmerican Journal of Transplantation, 2009